The influence of nrf2 on cardiac responses to environmental stressors.
Hypoxia and particulate matter caused more heart rate variability in Nrf2 knockout mice.
Could this help to explain the chronic heart rate variability issues in CFS, if CFS patients have Nrf2 inhibited for some reason (HSP, genetics, mold toxins, etc.)?
"Results demonstrate that Nrf2 deletion increases susceptibility to change in HR and HRV responses to environmental stressors and suggest potential therapeutic strategies to prevent cardiovascular alterations."
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