"The Nrf2-ARE pathway appears to contribute to neuroprotection. First, activation of the Nrf2-ARE pathway by tert-butylhydroquinone (tBHQ) protected neuroblastoma cells from oxidative glutamate toxicity (27)"
"Overexpression of Nrf2 and small molecule-mediated activation of the Nrf2-ARE pathway in astrocytes increased resistance of neurons to non-excitotoxic glutamate toxicity (31)"
NRf2 - A multi-organ protector?
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